Thermo Fisher Scientific MMP3 Monoclonal Antibody (SL-1 ID3), Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

2-4 µg/mL

-

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

SL-1 ID3

Immunogen

APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10986052

Product Specific Information

MA5-14199 targets MMP-3 (Stromelysin-1) in IF and WB applications and shows reactivity with Human samples.

The MA5-14199 immunogen is aPMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1).

Target Information

MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.