Thermo Fisher Scientific Integrin alpha 3 Polyclonal Antibody
Integrin alpha 3에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Pig, Rat에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Integrin alpha 3, amino acids 976–1025 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ITGA3 (Integrin alpha 3), also known as CD49C, VLA3, or GAPB3, is encoded by the ITGA3 gene on chromosome 17q21.33. It is an integrin alpha subunit and a member of the cell surface adhesion molecule family. ITGA3 forms the α3β1 integrin complex, which plays a key role in neural migration and corticogenesis in conjunction with the β1 subunit.
Phosphorylation of DAB1 and ITGA3 signaling regulate neuronal detachment from radial glial fibers. Expression of human ITGA3 enhances viral infectivity in Chinese hamster ovary cells. ITGA3 possesses 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units typical of integrins. Recombinant ITGA3 appears as a 150-kD protein, identical in size to the native form by western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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