Thermo Fisher Scientific SYNGR3 Polyclonal Antibody
Human SYNGR3 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000~1:2,500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 시약이며, 4°C 단기 및 -20°C 장기 보관. 신경전달물질 방출 조절 연구에 적합.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SYNGR3. Recombinant protein control fragment (Product #RP-99856). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648137 |
Product Specific Information
Immunogen sequence:
KALQRFRLGT DMSLFATEQL STGASQAYPG YPVGSGVEGT ETYQSPPFTE TLDTSPKGYQ VP
Antigen sequence identity:
- Mouse: 94%
- Rat: 35%
Target Information
Synaptogyrins are a family of tyrosine-phosphorylated membrane proteins with two neuronal members (SYNGR1 and SYNGR3) and one ubiquitous member (SYNGR2).
- SYNGR1 and SYNGR3: Synaptic vesicle proteins involved in neurotransmitter release regulation.
- SYNGR2: Absent from synaptic vesicles.
- SYNGR4: Role and localization unclear.
SYNGR3 is predominantly expressed in brain and placenta and plays a role in the positive regulation of dopamine transporter activity. It facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, enabling efficient vesicle loading with extracellular dopamine after release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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