Thermo Fisher Scientific CLASP2 Polyclonal Antibody
인간 CLASP2 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 IP 실험에 적합하며, Protein G로 정제된 비결합형 액상 포맷. PBS/glycerol buffer에 보관하며, 세포 이동 및 미세소관 안정화 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:200 |
| Immunoprecipitation (IP) | 1:200–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CLIP-associating protein 2 (226–381 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C or -80°C (preferred) |
| Shipping Conditions | Wet ice |
| RRID | AB_2902089 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
CLASP2 is a microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. It is required for the polarization of cytoplasmic microtubule arrays in migrating cells toward the leading edge. CLASP2 acts at the cell cortex to enhance the rescue frequency of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This activity is regulated in part by phosphatidylinositol 3-kinase signaling and also functions at the kinetochore, essential for bipolar chromosome alignment on the mitotic spindle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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