Thermo Fisher Scientific PPP3CC Polyclonal Antibody
Thermo Fisher Scientific PPP3CC Polyclonal Antibody는 인간 PPP3CC 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP3CC. Recombinant protein control fragment (Product #RP-93771). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789986 |
Product Specific Information
Immunogen sequence:
RGFSLQHKIR SFEEARGLDR INERMPPRKD SIHAGGPMKS VTSAHSHAAH RSDQGKKAHS
Target Information
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation, and a unique form of calcineurin appears to be associated with the flagellum.
The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least three genes—calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3)—have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90–95% amino acid identity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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