Thermo Fisher Scientific Dynamin 2 Polyclonal Antibody
Dynamin 2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. Human, Mouse, Rat 반응성 확인. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:10,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 100–334 of Human Dynamin 2 (UniProt ID: P50570-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.06 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547133 |
Product Specific Information
- Recommended positive controls: A549, HeLa, mouse brain, PC-12, Rat-2, rat brain
- Predicted reactivity: Mouse (99%), Rat (98%), Xenopus laevis (90%), Rhesus Monkey (100%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Dynamins are a subfamily of GTP-binding proteins sharing sequence similarity in the N-terminal GTPase domain. They are associated with microtubules and involved in processes such as endocytosis, cell motility, and membrane remodeling (e.g., bone resorption by osteoclasts). Dynamins interact with actin-binding and cytoskeletal proteins and can self-assemble, enhancing GTPase activity. Multiple alternatively spliced transcripts exist, encoding different protein variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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