Thermo Fisher Scientific ZMYM4 Polyclonal Antibody
인간 ZMYM4 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 완충액에 보관되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZMYM4. Recombinant protein control fragment (Product #RP-101349). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649939 |
Product Specific Information
Immunogen sequence:
WEEELNHYAL KSNAVQEADS ELKQFSKGET EQDLEADFPS DSFDPLNKGQ GIQARSRTRR RHRDGFPQPR RRGRKKSIVA VEPRSLI
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. Protein folding and DNA-binding ability are governed by the coordination of a zinc ion. ZMYM4 is overexpressed in human lung adenocarcinomas and squamous cell carcinomas. Overexpression of a fragment of the 3′UTR of the ZMYM4 mRNA, termed Cell Death Inhibiting RNA (CDIR), protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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