Thermo Fisher Scientific RRP8 Polyclonal Antibody
인간 RRP8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 4°C에서 보관, 연구용 전용.
- 카탈로그번호
- A304201A
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RRP8 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of Human Ribosomal RNA Processing 8 (RRP8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
RRP8 is an essential component of the eNoSC (energy-dependent nucleolar silencing) complex, which mediates silencing of rDNA in response to intracellular energy status by recruiting histone-modifying enzymes.
Upon glucose starvation, increased NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation and subsequent dimethylation of H3 at Lys-9 (H3K9me2) by SUV39H1, forming silent chromatin in the rDNA locus.
Within the complex, RRP8 binds to H3K9me2 and likely acts as a methyltransferase, though its substrates remain unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.