Thermo Fisher Scientific p19 INK4d Polyclonal Antibody
Thermo Fisher Scientific의 p19 INK4d Polyclonal Antibody는 인간 및 설치류 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot에 최적화되어 있으며, 세포 주기 조절 연구에 적합합니다. 2 mg/mL 농도의 액상 형태로 제공되며, 단백질 A로 정제되었습니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–165 of Human p19 INK4d |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2545180 |
Product Specific Information
- Recommended positive controls: Rat bone marrow
- Predicted reactivity: Mouse (88%), Rat (88%), Rhesus Monkey (98%), Bovine (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
p19 is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein forms a stable complex with CDK4 or CDK6 to prevent activation of CDK kinases, functioning as a cell growth regulator controlling G1 progression. The transcript abundance oscillates in a cell-cycle dependent manner, with lowest expression at mid G1 and maximal expression during S phase. This protein’s negative regulation of the cell cycle contributes to repression of neuronal proliferation and spermatogenesis.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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