Thermo Fisher Scientific Endothelin 3 Monoclonal Antibody (OTI3E10)
Endothelin 3 단백질을 인식하는 Thermo Fisher의 단클론 항체로, 인간 시료에 반응합니다. IHC(P)에서 1:150 희석 비율로 사용 가능하며, 고순도의 Affinity Chromatography 정제 제품입니다. -20°C 보관, 연구용 전용입니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 17–238 of EDN3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723124 |
Target Information
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in various biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. It acts as a ligand for endothelin receptor type B (EDNRB), essential for the development of neural crest-derived lineages such as melanocytes and enteric neurons. Mutations in this gene and EDNRB are associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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