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Thermo Fisher Scientific MLH1 Monoclonal Antibody (OTI2A8), TrueMAB
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Thermo Fisher Scientific MLH1 Monoclonal Antibody (OTI2A8), TrueMAB

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인간 MLH1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합. Affinity chromatography로 정제된 액상 제품이며, PBS/BSA/glycerol buffer에 보관. DNA mismatch repair 연구 및 MSI 관련 연구용으로 사용.

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마지막 업데이트 2025. 08. 05. 오후 12:45
Thermo Fisher Scientific TA811846 MLH1 Monoclonal Antibody (OTI2A8), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific MLH1 Monoclonal Antibody (OTI2A8), TrueMAB

Applications

Western Blot (WB)

  • Tested Dilution: 1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone OTI2A8
Immunogen Human recombinant protein fragment corresponding to amino acids 1–298 of human MLH1 produced in E. coli
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions −20 °C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

MLH1 is a DNA mismatch repair protein essential for maintaining genetic stability. Defects in this pathway can lead to microsatellite instability (MSI), which is associated with carcinogenesis. Mutations in mismatch repair genes, including MLH1, are linked to hereditary nonpolyposis colon cancer (HNPC). MLH1 forms a heterodimer with PMSH after MSH2 binds to mismatched DNA, facilitating subsequent repair steps.


For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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