Thermo Fisher Scientific SEMA3E/Semaphorin 3E Polyclonal Antibody
SEMA3E/Semaphorin 3E에 특이적인 Rabbit Polyclonal Antibody로 다양한 종(Human, Mouse, Rat)에 반응합니다. WB, IHC, ICC, ELISA 등 여러 응용에 적합하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용되며 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SEMA3E/Semaphorin 3E, amino acids 401–450 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Semaphorins are the largest family of axon guidance cues known. They are divided into eight classes, with classes 3–7 found in vertebrates.
- Class 3 Semaphorins are secreted proteins.
- Classes 4–6 are transmembrane proteins.
- Class 7 is membrane-associated via glycosylphosphatidylinositol (GPI) linkage.
Semaphorins share a conserved ~400 amino acid sema domain and are known as collapsing factors and mediators of axon repulsion, while also functioning as context-dependent chemoattractants. They play roles in cardiovascular development and immune cell antigen presentation. Their signaling is mediated by Neuropilin and Plexin receptor families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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