Thermo Fisher Scientific CRISP3 Monoclonal Antibody (295203)

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): 8–25 µg/mL

Product Specifications

Product Specific Information

• In direct ELISAs and Western blots, 50–100% cross-reactivity with recombinant human CRISP-2 is observed.
• Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Cysteine-rich secretory protein 3 (CRISP-3; also known as SGP28) is a glycoprotein belonging to the cysteine-rich secretory protein (CRISP) family, originally discovered in human neutrophilic granulocytes.
CRISP-3 is widely distributed in exocrine glands (salivary glands, pancreas, and prostate), eosinophilic granulocytes, and to a lesser extent in epididymis, ovary, thymus, and colon.
Its presence in neutrophils, eosinophils, and exocrine secretions suggests a role in innate host defense.
This antibody was raised against a recombinant C-terminally truncated form of CRISP-3 and recognizes both N-glycosylated and non-glycosylated forms of the mature protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.