
Thermo Fisher Scientific CRISP3 Monoclonal Antibody (295203)
인간 CRISP3 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P) 등에 사용 가능. 0.5 mg/mL 농도로 동결건조 형태로 제공되며, PBS + 5% trehalose 완충액에 보관. 인간 CRISP-2와 일부 교차반응을 나타냄.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 295203 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human CRISP-3 Asn21–Tyr245 (Ser106Pro and Ala134Ser) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608535 |
Product Specific Information
- In direct ELISAs and Western blots, 50–100% cross-reactivity with recombinant human CRISP-2 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Cysteine-rich secretory protein 3 (CRISP-3; also known as SGP28) is a glycoprotein belonging to the cysteine-rich secretory protein (CRISP) family, originally discovered in human neutrophilic granulocytes.
CRISP-3 is widely distributed in exocrine glands (salivary glands, pancreas, and prostate), eosinophilic granulocytes, and to a lesser extent in epididymis, ovary, thymus, and colon.
Its presence in neutrophils, eosinophils, and exocrine secretions suggests a role in innate host defense.
This antibody was raised against a recombinant C-terminally truncated form of CRISP-3 and recognizes both N-glycosylated and non-glycosylated forms of the mature protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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