Thermo Fisher Scientific COX6C Monoclonal Antibody (S51)
인간 COX6C 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, ELISA에 사용 가능. Affinity chromatography로 정제된 액상형 제품이며, 보존제 무첨가. -20°C 보관, 반복 동결 해동 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | S51 |
| Immunogen | COX6C (AAH00187, 1 a.a.–75 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MAPEVLPKPR MRGLLARRLR NHMAVAFVLS LGVAALYKFR VADQRKKAYA DFYRNYDVMK DFEEMRKAGI FQSVK
Target Information
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially encoded subunits function in electron transfer, while the nuclear-encoded subunits may be involved in the regulation and assembly of the complex.
This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with the mouse subunit VIc and is up-regulated in prostate cancer cells. A pseudogene has been found on chromosome 16p12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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