Thermo Fisher Scientific CD19 Monoclonal Antibody (eBio1D3 (1D3)), PerCP-Cyanine5.5, eBioscience

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: -
• Publications: View 1 publication

Flow Cytometry (Flow)

• Tested Dilution: 0.25 µg/test
• Publications: View 93 publications

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 561, 660, 700
• APC, APC-eFluor 780
• Biotin
• Brilliant UV / Violet / Yellow series
• eFluor 450, 506, 660
• FITC
• Functional Grade
• NovaFluor Blue / Red / UV / Violet / Yellow series
• PE, PE-Cyanine5, PE-Cyanine5.5, PE-Cyanine7, PE-eFluor 610
• Super Bright 436, 600, 645, 702, 780
• Request custom conjugation available

Product Specific Information

The eBio1D3 monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane glycoprotein expressed by B cells during all stages of development except plasma cells. CD19 forms complexes with CD21, CD81, and MHC class II, contributing to BCR signaling and B cell proliferation.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Mouse splenocytes; ≤ 0.25 µg/test
• Recommended Conditions: 100 µL final volume per test; cell number 10⁵–10⁸ cells/test
• Excitation/Emission: 488 nm / 695 nm (Blue Laser)
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on all peripheral B cells and certain myeloid leukemia cells. CD19 serves as a key regulator of B cell activation and proliferation, functioning as a signal-amplifying coreceptor for the BCR. Mutations can lead to hypogammaglobulinemia, while overexpression may cause B cell hyperactivity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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