Thermo Fisher Scientific CD23 Monoclonal Antibody (5B5)
Human CD23(FcεRII) 인식용 Mouse IgG1 단클론 항체로 ELISA 및 Flow Cytometry에 적합. 비결합형 액상 형태이며 0.03% sodium azide 포함. 4°C 단기, -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B5 |
| Immunogen | Purified recombinant fragment of human FCER2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10979856 |
Product Specific Information
MA5-15728 targets FCER2 in indirect ELISA and FACS applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human FCER2 expressed in E. coli.
MA5-15728 detects FCER2, which has a predicted molecular weight of approximately 37 kDa.
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of peripheral blood and tonsil B cells and is strongly expressed on EBV-transformed B lymphoblasts.
It is identical to the low-affinity IgE receptor found on B cells.
CD23 expression has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some centroblastic/centrocytic lymphomas.
Functionally, CD23 is involved in B cell growth, differentiation, and IgE production.
A soluble form of CD23 acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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