Thermo Fisher Scientific ARAP1 Polyclonal Antibody
인간 ARAP1 단백질을 검출하는 Thermo Fisher Scientific의 폴리클로날 항체. IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품. PBS/glycerol 저장용액에 보관하며 -20°C에서 안정적 저장 가능.
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- PA550604
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636057 |
Product Specific Information
The antibody detects endogenous levels of total ARAP1 protein.
Target Information
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeats. This adaptor serves as a link between phosphoinositide-, Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and also regulates trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, promoting TRAIL-induced apoptosis in certain cell types. Additionally, ARAP1 influences cell spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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