Thermo Fisher Scientific ANP32C Monoclonal Antibody (OTI10A10), TrueMAB
ANP32C 단백질을 표적으로 하는 Mouse 모노클로날 항체로 Western blot, IHC, Flow cytometry에 사용 가능. 고순도 Affinity chromatography 정제. PBS/BSA/glycerol buffer에 보관되며 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10A10 |
| Immunogen | Full length human recombinant protein of human ANP32C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ANP32C (acidic (leucine-rich) nuclear phosphoprotein 32 family, member C)
Also known as PP32R1 (phosphoprotein 32-related protein 1) or tumorigenic protein pp32r1, ANP32C is a 234 amino acid protein containing four leucine-rich repeats and belonging to the ANP32 family.
ANP32C shares 87.7% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits several cancers such as prostate and breast cancers. Unlike ANP32A, ANP32C is tumorigenic and expressed in activated stem cells (mobilized CD34+ and cord blood CD34+ cells), but not in resting bone marrow CD34+ cells. It is also expressed in various neoplastic cell lines, particularly prostatic adenocarcinoma, but not in normal prostatic tissue, suggesting a potential role in modulating oncogenic potential in human prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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