Thermo Fisher Scientific CD3 Monoclonal Antibody (UCHT1), PerCP-Cyanine5.5
인간 및 비인간 영장류의 CD3 복합체 ε-체인에 반응하는 단클론 항체. PerCP-Cyanine5.5 형광 접합으로 유세포분석(Flow Cytometry)에 최적화. PBS/BSA 완충액에 보관하며 4°C 암소 저장. 연구용으로만 사용.
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Thermo Fisher Scientific CD3 Monoclonal Antibody (UCHT1), PerCP-Cyanine5.5
Applications
- Flow Cytometry (Flow)
Tested Dilution: 4 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UCHT1 |
| Immunogen | Human thymocytes followed by Sezary T cells |
| Conjugate | PerCP-Cyanine5.5 |
| Excitation / Emission Max | 489 / 679 nm |
| Form | Liquid |
| Concentration | Not determined |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898618 |
Additional Formats
- APC
- APC-Cyanine7
- FITC
- PE
- PerCP
- Request custom conjugation available
Product Specific Information
This antibody reacts with the epsilon chain of the CD3 complex.
Target Information
The CD3 subunit complex is crucial for transducing antigen-recognition signals into T cells and regulating the surface expression of the TCR complex. CD3 activation involves the cytoplasmic tails of subunits (γ, δ, ε, ζ), which contain tyrosine-based motifs mediating signal transduction. CD3 is expressed on most peripheral blood lymphocytes and thymocytes, but not on B or NK cells. It is associated with T cell activation, growth regulation, and immune signaling. Genes encoding CD3 ε, γ, and δ are located on chromosome 11. Defects in CD3 are linked to immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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