Thermo Fisher Scientific DSC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 480-690 of human DSC1 (NP_0777391) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DSC1,uniProtId:Q08554-1,ncbiNodeId:9606,antigenRange:480-690,antigenLength:894,antigenImageFileName:PA5-87603_DSC1_Q08554-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87603_DSC1_Q08554-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.29 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804282

Product Specific Information

Immunogen sequence: SQDGFPAGQE LLGYKALDPE ISSGEGLRYQ KLGDEDNWFE INQHTGDLRT LKVLDRESKF VKNNQYNISV VAVDAVGRSC TGTLVVHLDD YNDHAPQIDK EVTICQNNED FAVLKPVDPD GPENGPPFQF FLDNSASKNW NIEEKDGKTA ILRQRQNLDY NYYSVPIQIK DRHGLVATHM LTVRVCDCST PSECRMKDKS TRDVRPNVIL G; Positive Samples: Raji, Mouse liver, Rat liver; Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome

Target Information

The desmosomal cadherin desmocollin DSC1 is expressed in upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein (4) required for strong adhesion and barrier maintenance in epidermis and contributes to epidermal differentiation.The DSC1 gene comprises 17 exons spanning approximately 33 kb on 18q12.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.