Thermo Fisher Scientific DSC1 Polyclonal Antibody
DSC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 고순도의 Affinity Chromatography로 정제되었습니다. 세포막 및 데스모솜 단백질 연구용으로 활용됩니다.
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- PA587603
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 480–690 of human DSC1 (NP_0777391) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804282 |
Product Specific Information
Immunogen sequence:
SQDGFPAGQE LLGYKALDPE ISSGEGLRYQ KLGDEDNWFE INQHTGDLRT LKVLDRESKF VKNNQYNISV VAVDAVGRSC TGTLVVHLDD YNDHAPQIDK EVTICQNNED FAVLKPVDPD GPENGPPFQF FLDNSASKNW NIEEKDGKTA ILRQRQNLDY NYYSVPIQIK DRHGLVATHM LTVRVCDCST PSECRMKDKS TRDVRPNVIL G
Positive Samples: Raji, Mouse liver, Rat liver
Cellular Location: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome
Target Information
The desmosomal cadherin DSC1 is expressed in the upper epidermis where strong adhesion is required. DSC1 is a type I membrane protein essential for strong adhesion and barrier maintenance in the epidermis, contributing to epidermal differentiation.
The DSC1 gene comprises 17 exons spanning approximately 33 kb on chromosome 18q12.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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