Thermo Fisher Scientific eIF2alpha/EIF2S1 Polyclonal Antibody
Rabbit polyclonal antibody against human eIF2alpha/EIF2S1 for IHC and IHC-P applications. Reacts with multiple species. Antigen affinity purified, unconjugated liquid form. Stable for 1 year at 4°C, shipped on wet ice.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:50–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 and the C-terminus (residue 315) of human Eukaryotic Translation Initiation Factor 2, subunit 1 alpha (EIF2S1), 35 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Bovine, Dog, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and African elephant
Target Information
EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives the binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: IHC-00456_EIF2S1_P05198-1_Rabbit.svg, IHC-00456_EIF2S1_P05198-1_Rabbit_PDP.jpeg)
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