Thermo Fisher Scientific eEF1G Polyclonal Antibody
Rabbit polyclonal antibody recognizing eEF1G in human and mouse. Suitable for IHC and IHC (Paraffin) applications. Antigen affinity purified with 0.25 mg/mL concentration. Supplied in TBS buffer with BSA and sodium azide. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:50–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 200 and 250 of human Eukaryotic Translation Elongation Factor 1 Gamma (EEF1G, UniProt ID: P26641-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, and Crab-eating macaque
Target Information
EF-1 (elongation factor-1) is a multi-protein complex responsible for delivering aminoacyl-tRNAs to the ribosome.
EF-1 gamma (EEF1G or GIG35) is a 437 amino acid subunit of this complex. It is expressed in the stomach, pancreas, brain, lung, kidney, intestine, liver, and spleen.
EF-1 gamma contains an N-terminal Glutathione transferase domain that may anchor the complex to cellular components and play a role in assembling multiprotein complexes with aminoacyl-tRNA synthetases.
Increased expression of EF-1 gamma has been associated with pancreatic cancer, suggesting a potential role in oncogenic transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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