Thermo Fisher Scientific Acetyl CoA Carboxylase Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합한 Acetyl CoA Carboxylase 폴리클로날 항체. 사람, 생쥐, 랫트 반응성. Protein A 정제, 1 mg/mL 농도. 지방산 합성 연구용 효소 타깃 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Acetyl CoA Carboxylase (amino acids 2307–2355) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system and a biotin-containing enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by different genes. ACC-alpha is enriched in lipogenic tissues. The enzyme is regulated at transcriptional and translational levels, and through phosphorylation/dephosphorylation of serine residues and allosteric modulation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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