Thermo Fisher Scientific PEX19 Polyclonal Antibody
PEX19 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human 및 Mouse에 반응하며 항원 친화 크로마토그래피로 정제됨. 세포 내 퍼옥시좀 생합성 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PEX19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792557 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (88%), Rat (90%), Bovine (92%).
- Positive Control: Jurkat, Raji, NCI-H929.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The PEX19 gene is essential for early peroxisomal biogenesis. It functions as both a cytosolic chaperone and an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are critical for the assembly of functional peroxisomes.
Peroxisome biogenesis disorders (PBDs) are genetically heterogeneous, autosomal recessive diseases characterized by multiple defects in peroxisome function. These disorders include at least 14 complementation groups, with variable phenotypes observed within groups.
Cells from PBD patients exhibit defects in importing one or more classes of peroxisomal matrix proteins. Mutations in this gene are associated with Zellweger syndrome (ZWS).
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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