Thermo Fisher Scientific SMARCC2 Polyclonal Antibody
SMARCC2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 IHC(P) 적용 가능. 인간, 마우스, 랫트 반응성. 고순도 항원 친화 크로마토그래피 정제 제품으로 장기 보관 시 -20°C 권장. 연구용 전용.
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Thermo Fisher Scientific SMARCC2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human SMARCC2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.67 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792556 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (95%), Xenopus laevis (83%), Bovine (99%).
- Positive Control: MCF-7, MDA-MB-231.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways.
Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9.
PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation.
The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription.
In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control.
Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-85414_SMARCC2_Q8TAQ2-1_Rabbit.svg
- PA5-85414_SMARCC2_Q8TAQ2-1_Rabbit_PDP.jpeg
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