Thermo Fisher Scientific Cathepsin K Polyclonal Antibody
Cathepsin K 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성을 가지며 WB 및 ELISA에 적합합니다. 고순도 Affinity Chromatography로 정제되어 안정적인 액상 형태로 제공됩니다. 연구용으로 골 재형성 및 암 침습 관련 연구에 활용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 115–329 of human CTSK (NP_000387.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.24 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855017 |
Product Specific Information
Immunogen sequence:
APDSVDYRKK GYVTPVKNQG QCGSCWAFSS VGALEGQLKK KTGKLLNLSP QNLVDCVSEN DGCGGGYMTN AFQYVQKNRG IDSEDAYPYV GQEESCMYNP TGKAAKCRGY REIPEGNEKA LKRAVARVGP VSVAIDASLT SFQFYSKGVY YDESCNSDNL NHAVLAVGYG IQKGNKHWII KNSWGENWGN KGYILMARNK NNACGIANLA SFPKM
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, a member of the peptidase C1 family, is predominantly expressed in osteoclasts. It is also found in a fraction of human breast cancers, potentially contributing to tumor invasiveness. Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-109606_Cathepsin_K_P43235-1_Rabbit.svg)
(이미지: PA5-109606_Cathepsin_K_P43235-1_Rabbit_PDP.jpeg)
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