Thermo Fisher Scientific JAKMIP1 Polyclonal Antibody
JAKMIP1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간, 생쥐, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 신경 및 림프계 연구용으로 적합한 고품질 연구용 항체입니다.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the center of human JAKMIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551847 |
Product Specific Information
A suggested positive control is rat brain tissue lysate.
PA5-34495 can be used with blocking peptide PEP-1537.
Target Information
JAKMIP1 (Marlin-1) is a highly conserved, vertebrate-specific microtubule-associated protein involved in JAK1 signaling and microtubule cytoskeleton regulation.
It is predominantly expressed in neuronal and lymphoid cells, colocalizing with microtubules.
Multiple isoforms exist:
- Isoforms 1 and 5: expressed in liver, lung, and skeletal muscle
- Isoforms 2–4: expressed in brain and retina
JAKMIP1 participates in polarized secretion in lymphocytes and may act as a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of its expression has been associated with autism-related genetic conditions in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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