Thermo Fisher Scientific POLR1C Polyclonal Antibody
POLR1C 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 면역세포염색에 적합하며, 인간과 생쥐 시료에서 반응. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific POLR1C Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POLR1C (Accession O15160), corresponding to amino acid residues D103–A153. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850996 |
Product Specific Information
Antibody detects endogenous levels of total POLR1C.
Target Information
RNA polymerases transcribe nuclear genes for ribosomal RNA, thus representing ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
Different subunits of the Pol I transcription machinery are targets of various physiological stimuli, suggesting that multiple signaling pathways are involved in Pol I transcription.
RPA16, RPA40, and RPA135 are subunits of Pol I that associate at an early stage of RNA Pol I assembly.
RPA40 is essential for the function and integrity of the complex and is also an essential subunit of RNA polymerase III (Pol III).
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-101562_POLR1C_O15160-1_Rabbit.svg / PA5-101562_POLR1C_O15160-1_Rabbit_PDP.jpeg)
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