Thermo Fisher Scientific NEFM Polyclonal Antibody
NEFM 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 대부분의 포유류에 반응하며, 신경세포 마커 연구에 적합. 4°C 단기 보관, -20°C 장기 보관 권장.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NEFM Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:1,000–1:2,500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 1:1,000–1:2,500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Chicken, Horse, Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M (amino acids 549–845) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 5 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2150065 |
Product Specific Information
This antibody is likely to react with most mammals.
Suggested positive control: antigen standard for NEFM (transient overexpression lysate).
Target Information
Neurofilaments (NFs) are intermediate filaments expressed almost exclusively in neuronal cells, particularly in large axons.
They are composed of three major subunits — NF-M (medium), NF-H (high), and NF-L (light) — which share a coiled-coil core domain but differ in the length and sequence of their termini.
The NF-M protein tail domain mediates neurofilament interactions critical for axonal size and cytoskeletal architecture.
Phosphorylation and O-GlcNAcylation of NF-M regulate its translocation, filament formation, and function.
Antibodies against neurofilament subunits serve as valuable neuronal markers due to their abundance, neuron-specific expression, and biochemical stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.