Thermo Fisher Scientific alpha Internexin Polyclonal Antibody
다양한 종에서 반응하는 알파 인터넥신 폴리클로날 항체로, 신경세포 발달 연구에 적합. Western blot, IHC, ICC/IF, IP 등 다양한 응용 가능. 비결합형 액상 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:500–1:1,000 |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Human, Mammal, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified recombinant rat α-internexin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2127367 |
Target Information
Alpha-internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the neurofilament triplet proteins (NF-L, NF-M, NF-H), sharing similar protein motifs and intron organization. Many mature neurons contain α-internexin alongside these proteins, while some express only α-internexin.
Antibodies to internexin are valuable tools for studying and classifying neuronal types and tracing neuronal processes in tissue sections or cultures. Its early developmental expression makes α-internexin a convenient marker for neuronal progenitor cells and cells committed to the neuronal lineage. Potential applications in brain tumor research remain to be explored.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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