Thermo Fisher Scientific SKIV2L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SKIV2L. Recombinant protein control fragment (Product #RP-99550). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SKIV2L,uniProtId:Q15477-1,ncbiNodeId:9606,antigenRange:786-886,antigenLength:1246,antigenImageFileName:PA5-62520_SKIV2L_Q15477-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62520_SKIV2L_Q15477-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647333

Product Specific Information

Immunogen sequence: LAELTKRLGA LEEPDMTGQL VDLPEYYSWG EELTETQHMI QRRIMESVNG LKSLSAGRVV VVKNQEHHNA LGVILQVSSN STSRVFTTLV LCDKPLSQDP Q

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

Target Information

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.