Thermo Fisher Scientific RHBDD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RHBDD2. Recombinant protein control fragment (Product #RP-100184). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RHBDD2,uniProtId:Q6NTF9-1,ncbiNodeId:9606,antigenRange:208-281,antigenLength:364,antigenImageFileName:PA5-62521_RHBDD2_Q6NTF9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62521_RHBDD2_Q6NTF9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646525

Product Specific Information

Immunogen sequence: ERVALKLDQT FPFSLMRRIS VFKYVSGSSA ERRAAQSRKL NPVPGSYPTQ SCHPHLSPSH PVSQTQHASG QKLA

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 84%.

Target Information

The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. Little is known about the role of RHBDD2. Its overexpression in breast carcinoma appears to be an indicator of poor prognosis and may play a role in breast cancer progression. The related proteins RHBDD1 and RHBDD3 are both involved in the regulation of apoptosis, suggesting that RHBDD2 may also be involved in the modulation of apoptotic activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.