Thermo Fisher Scientific BTF Polyclonal Antibody
Thermo Fisher Scientific의 BTF Polyclonal Antibody는 인간 BCLAF1 단백질을 인식하는 Rabbit IgG 폴리클론 항체입니다. Western blot, IHC, IP 등에 사용 가능하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
Immunoprecipitation (IP)
- Tested Dilution: 1–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 150–200 of human BCL2-Associated Transcription Factor 1 (BCLAF1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
BCLAF1 is an intracellular, death-promoting transcriptional repressor of survival genes that interacts with several members of the BCL2 family of proteins.
It shows homology to the basic leucine zipper (bZIP) and MYB DNA-binding domains.
In apoptotic cells, BCLAF1 localizes to dot-like structures throughout the nucleus and redistributes near the nuclear envelope.
Overexpression induces apoptosis, which can be suppressed by co-expression of BCL2 proteins.
Also known as BTF, it triggers a proapoptotic signal and may help overcome resistance to STI571.
BCLAF1 is predominantly expressed in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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