Thermo Fisher Scientific ALKBH5 Recombinant Rabbit Monoclonal Antibody (10H24L9)

Applications

Western Blot (WB)

• Tested Dilution: 1:5,000
• View 2 publications

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, and Pig.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages include:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the larger rabbit immune repertoire

Target Information

ALKBH5 (RNA demethylase ALKBH5) is a dioxygenase that demethylates RNA by oxidative demethylation.
It specifically removes N(6)-methyladenosine (m6A) from RNA, the most prevalent internal modification in eukaryotic mRNA.
Demethylation of m6A affects mRNA processing and export. ALKBH5 can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro).
It requires molecular oxygen, alpha-ketoglutarate, and iron for activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.