Thermo Fisher Scientific VAV3 Polyclonal Antibody
Rabbit에서 유래한 VAV3 폴리클로날 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 VAV3 Tyr173 비인산화 펩타이드로부터 합성된 면역원 사용. 액상 형태로 제공되며 -20°C에 보관, 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA539838
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: - [References]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
- Publications: - [References]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic non-phosphopeptide derived from human VAV3 around the phosphorylation site of Tyr173 (E-V-YP-E-D) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556387 |
Target Information
This gene is a member of the VAV gene family.
VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations.
This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent RAC1, and it associates maximally with the nucleotide-free states of these GTPases.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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