Thermo Fisher Scientific TUBA1/3/4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TUBA1/3/4 proteins. Validated for WB, IHC, and ICC applications. Unconjugated, liquid form with 1 mg/mL concentration. Ideal for studying microtubule structure and function in eukaryotic cells.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic non-phosphopeptide derived from human TUBA1/3/4 around Tyr272 (A-T-YP-A-P) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556385 |
Target Information
Alpha Tubulin is part of a heterodimer consisting of alpha and beta tubulin subunits, each approximately 55 kDa. These subunits form microtubules—cylindrical filamentous structures found in nearly all eukaryotic cells. Microtubules provide structural support, enable intracellular transport, and play a vital role during mitosis.
Eukaryotic microtubules are composed of alpha and beta tubulins, with gamma tubulin facilitating microtubule nucleation. Multiple alpha and beta tubulin genes are highly conserved among species. The alpha tubulin gene shows strong similarity to the mouse and rat Tuba1 gene. Northern blot analyses indicate predominant expression in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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