Thermo Fisher Scientific DGCR8 Recombinant Rabbit Monoclonal Antibody (ARC0289)
DGCR8 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot 및 ELISA에 적합하며, 인간과 생쥐 시료에 반응. 고순도의 액상 항체로, 안정적인 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0289 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 436–764 of human DGCR8 (Q8WYQ5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898018 |
Product Specific Information
- Positive Samples: HeLa, RD, U-251MG, Mouse brain
- Immunogen sequence:
DLEEFRSYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA NQKLITLSVQ DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS VTIDGVTYGS GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED SRVYELTSKA GLLSPYQILH ECLKRNHGMG DTSIKFEVVP GKNQKSEYVM ACGKHTVRGW CKNKRVGKQL ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN KPNLHILSKL QEEMKRLAEE REETRKKPKM SIVASAQPG
Target Information
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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