Thermo Fisher Scientific DGCR8 Recombinant Rabbit Monoclonal Antibody (ARC0289)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0289

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 436-764 of human DGCR8 (Q8WYQ5) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DGCR8,uniProtId:Q8WYQ5-1,ncbiNodeId:9606,antigenRange:436-764,antigenLength:773,antigenImageFileName:MA5-38100_DGCR8_Q8WYQ5-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38100_DGCR8_Q8WYQ5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898018

Product Specific Information

Positive Samples: HeLa, RD, U-251MG, Mouse brain

Immunogen sequence: DLEEFRSYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA NQKLITLSVQ DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS VTIDGVTYGS GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED SRVYELTSKA GLLSPYQILH ECLKRNHGMG DTSIKFEVVP GKNQKSEYVM ACGKHTVRGW CKNKRVGKQL ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN KPNLHILSKL QEEMKRLAEE REETRKKPKM SIVASAQPG

Target Information

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.