
Thermo Fisher Scientific PTPRM Monoclonal Antibody (1H6D10)
Human PTPRM 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 ELISA에 적합. Protein G로 정제된 액상 형태이며, 1 mg/mL 농도. 세포 신호 조절 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6D10 |
| Immunogen | Purified recombinant fragment of human PTPRM (AA: extra 565–742) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787497 |
Product Specific Information
MA5-31874 has been tested in indirect ELISA.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP includes:
- Extracellular region with MAM domain, Ig-like domain, and four fibronectin type III-like repeats
- Single transmembrane region
- Two tandem catalytic domains
It mediates cell-cell aggregation via homophilic interaction and can interact with scaffolding protein RACK1/GNB2L1, contributing to downstream signaling during cell adhesion.
Alternative splicing produces multiple isoforms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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