Thermo Fisher Scientific Lyn Polyclonal Antibody
Rabbit polyclonal antibody against human LYN protein. Validated for WB, IHC(P), and Flow Cytometry. High specificity and sensitivity with 1.5 mg/mL concentration. Suitable for research use in cell signaling and kinase studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 32–62 amino acids from the N-terminal region of human LYN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2138249 |
Target Information
Lyn proto-oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well-studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells, with exclusion in T lymphocytes. Lyn plays diverse roles such as regulation of B cell receptor signaling, mast cell signaling, and epithelial–mesenchymal transition (EMT).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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