Thermo Fisher Scientific CYP7B1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

3-6 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (YPDSDVLFRYKVKS) corresponding to the C-terminus amino acids of CYP7B1 (aa 493-506). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CYP7B1,uniProtId:O75881-1,ncbiNodeId:9606,antigenRange:493-506,antigenLength:506,antigenImageFileName:PA5-18224_CYP7B1_O75881-1_Goat.svg,antigenImageFileNamePDP:PA5-18224_CYP7B1_O75881-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10981515

Product Specific Information

This antibody is predicted to react with bovine and human based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.

Preliminary analysis showed no signal in Western Blot.

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.