Thermo Fisher Scientific UBA6 Polyclonal Antibody
Western blot과 Immunoprecipitation에 적합한 Rabbit Polyclonal 항체. Human UBA6(UBE1L2) 단백질의 1002-1052번 영역을 면역원으로 제작. 액상 형태, 1 mg/mL 농도. 4°C 보관, 1년 유효기간. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1002 to 1052 of Human Ubiquitin-Like Modifier Activating Enzyme 6 (UBA6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
UBA6 (also known as UBE1L2, MOP-4) is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family.
It participates in the cascade that covalently attaches ubiquitin (Ub) to substrate proteins.
UBA6 activates ubiquitin by adenylating its carboxy-terminal glycine residue with ATP, then linking this residue to the side chain of a cysteine residue in E1, forming an ubiquitin–E1 thioester and releasing AMP.
Its isoforms influence spermatogenesis and male fertility, and UBA6 is highly expressed in human monocytes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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