Thermo Fisher Scientific SOCS3 Polyclonal Antibody, FITC
SOCS3 단백질을 표적하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP 등에 사용 가능. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피 정제 및 고순도. 연구용으로만 사용.
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Thermo Fisher Scientific SOCS3 Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 175–225 on human SOCS3 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine receptor signaling is negatively regulated by the SOCS (Suppressor of Cytokine Signaling) family, which includes eight members: SOCS-1, 2, 3, 4, 5, 6, 7, and CIS.
SOCS proteins consist of an N-terminal variable region, a central SH2 domain, and a C-terminal SOCS box motif.
They function as part of a negative feedback loop regulating cytokine signal transduction through STAT-induced transcriptional mechanisms.
Transcription of SOCS genes occurs rapidly in response to cytokines, and each member inhibits signaling in distinct ways.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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