Thermo Fisher Scientific SOCS3 Polyclonal Antibody, Biotin
SOCS3 단백질을 표적으로 하는 Thermo Fisher Scientific의 Biotin 결합 폴리클로날 항체. Western blot, ELISA, IP에 적합하며, 인간, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 고품질 연구용 항체.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 175–225 on human SOCS3 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokine receptor signaling is negatively regulated by a family of Src homology 2 (SH2) domain-containing adaptor molecules termed SOCS (Suppressor of Cytokine Signaling). There are eight known members: SOCS-1 to SOCS-7 and CIS. These proteins share a structure consisting of a variable N-terminal region, a central SH2 domain, and a C-terminal SOCS box motif. SOCS proteins function as part of a negative feedback loop that regulates cytokine signal transduction via STAT-induced transcriptional mechanisms. Transcription of SOCS genes is rapidly induced by cytokines, and each member modulates signaling in distinct ways.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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