Thermo Fisher Scientific eIF2 gamma Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

• Recommended positive controls: HeLa, HepG2, HCT116
• Predicted reactivity: Rat (100%), Zebrafish (98%), Xenopus laevis (97%), Bovine (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules.
The eukaryotic initiation complex is composed of three subunits — eIF2 alpha, eIF2 beta, and eIF2 gamma — which form a ternary complex with GTP and tRNA in the early stages of protein synthesis.
eIF2S3 (eukaryotic translation initiation factor 2, subunit 3), also known as eIF2G, is a 472 amino acid protein belonging to the gamma subfamily of GTP-binding elongation factor proteins.
Existing as a heterotrimer composed of alpha, beta, and gamma chains, eIF2S3 binds ribosomal subunits and catalyzes the formation of preinitiation complexes necessary for protein synthesis.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.