Thermo Fisher Scientific Cyclophilin B Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Cyclophilin B 폴리클로날 항체. Rabbit IgG 기반으로 높은 특이성과 재현성을 제공. 항원 친화 크로마토그래피로 정제되어 높은 순도 보장. Human 반응성, 예측된 다종 교차 반응성 보유. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cyclophilin B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–216 of Human Cyclophilin B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2548646 |
Product Specific Information
- Recommended positive controls: A431, HepG2
- Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (86%), Xenopus laevis (87%), Cat (97%), Chicken (92%), Rhesus Monkey (100%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Immunophilins are a family of soluble cytosolic receptors capable of binding to immunosuppressant agents such as cyclosporin A (CsA) or FK506.
Proteins binding FK506 are termed FK506 Binding Proteins (FKBPs), and those binding cyclosporin A are called cyclophilins (CyPs).
Both CyP:CsA and FKBP:FK506 complexes inhibit calcineurin, a calcium- and calmodulin-dependent protein phosphatase involved in T-cell activation, providing a mechanism for immunosuppression.
Immunophilins function as peptidyl-prolyl cis-trans isomerases (PPIase), facilitating protein folding by catalyzing slow proline isomerization steps.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.