Thermo Fisher Scientific UBE1L2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human UBE1L2. Recombinant protein control fragment (Product #RP-96591). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBE1L2,uniProtId:A0AVT1-1,ncbiNodeId:9606,antigenRange:753-838,antigenLength:1052,antigenImageFileName:PA5-57909_UBE1L2_A0AVT1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57909_UBE1L2_A0AVT1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649173

Product Specific Information

Immunogen sequence: LHLSFLQNAA KLYATVYCIP FAEEDLSADA LLNILSEVKI QEFKPSNKVV QTDETARKPD HVPISSEDER NAIFQLEKAI LSNEAT

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.

Target Information

UBA6 (UBE1L2, MOP-4) is a novel E1 enzyme specific for ubiquitin and belongs to the ubiquitin-activating E1 family. It is a part of the cascade to attach ubiquitin (Ub) covalently to substrate proteins. UBA6 activates ubiquitin by first adenylating its carboxy-terminal glycine residue with ATP and then linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Its isoforms influence spermatogenesis and male fertility. UBA6 is highly expressed in human monocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.