Thermo Fisher Scientific TSEN34 Polyclonal Antibody
Rabbit polyclonal antibody against human TSEN34, validated for ICC/IF. Recognizes recombinant human SEN34 fragment. Supplied as liquid form, unconjugated, purified via antigen affinity chromatography. Suitable for research use only, with stable storage...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SEN34 (Recombinant protein control fragment, Product #RP-106179) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664596 |
Product Specific Information
Immunogen sequence:
KLEQASGASSS QEAGSSQAAK EDETSDGQAS GEQEEAGPSS SQAGPSNGVA PLPRSALLVQ LATARPRPVK ARPLDWRVQS KDWPH
Highest antigen sequence identity to the following orthologs:
- Mouse: 75%
- Rat: 76%
Target Information
TSEN34 encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3′ end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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