Thermo Fisher Scientific ATP7A Polyclonal Antibody
Rabbit polyclonal antibody targeting human ATP7A, validated for ICC/IF at 0.25–2 µg/mL. Recognizes recombinant human ATP7A fragment. Unconjugated, purified by antigen affinity chromatography, supplied in PBS with glycerol and sodium azide. Suitable for...
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ATP7A. Recombinant protein control fragment (Product #RP-104848) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663155 |
Product Specific Information
Immunogen sequence:
LKTKGVTDIKI YPQKRTVAVT IIPSIVNANQ IKELVPELSL DTGTLEKKSG ACEDHSMAQA GEVVLKMKVE GMTCHSCTST I
Highest antigen sequence identity to the following orthologs:
- Mouse: 78%
- Rat: 76%
Target Information
ATP7A (Copper-transporting ATPase 1)
ATP7A is a transmembrane copper-translocating P-type ATPase essential for systemic copper absorption in the gut and reabsorption in the kidney. It is expressed in many tumor types and contributes to resistance against cisplatin and carboplatin. Mutations in ATP7A cause Menkes disease, a fatal disorder in early childhood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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