Thermo Fisher Scientific alpha Actinin Monoclonal Antibody (A1G2)
Thermo Fisher Scientific의 alpha Actinin Monoclonal Antibody (A1G2)는 인체, 생쥐, 랫트에 반응하는 단클론 항체로 다양한 면역분석(WB, IHC, ICC/IF, Flow)에 사용 가능. 비접합형 액상 형태이며 고순도 Protein A 정제. 세포골격 단백질 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | View 1 publication |
| Flow Cytometry (Flow) | 1:50–1:100 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1G2 |
| Immunogen | Recombinant protein within Human ACTN1 aa 388–619 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2890273 |
Target Information
Alpha Actinin 1 belongs to the spectrin gene superfamily, a diverse group of cytoskeletal proteins including alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles in different cell types:
- In nonmuscle cells, it is found along microfilament bundles and adherens-type junctions, binding actin to the membrane.
- In skeletal, cardiac, and smooth muscle cells, it localizes to the Z-disc and dense bodies, anchoring myofibrillar actin filaments.
This gene encodes a nonmuscle, cytoskeletal alpha actinin isoform and maps to the same site as the erythroid beta spectrin gene.
Three transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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