Thermo Fisher Scientific CDK1 Polyclonal Antibody
CDK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합. 인간에 반응하며 마우스, 랫, 보비인, 오랑우탄에서도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 225 and 275 of human Cyclin-Dependent Kinase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, and Orangutan
Target Information
CDK1 (Cell Division Control protein 1) is essential for the completion of START, the controlling event in the cell cycle required to initiate mitosis.
CDK1 serves as the catalytic subunit of the M-Phase Promoting Factor (MPF) complex that induces entry into mitosis and is conserved among eukaryotes.
Phosphorylation of Bcl-2 during G2/M phase arrest following photodynamic therapy with hypericin involves a CDK1-mediated signal that delays apoptosis.
CDK inhibitors such as NU2058 have demonstrated therapeutic potential in androgen-independent prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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